diff --git a/classes/comparator.js b/classes/comparator.js
index 647c1f09..50856b2f 100644
--- a/classes/comparator.js
+++ b/classes/comparator.js
@@ -95,6 +95,15 @@ class Comparator {
 
     options = parseOptions(options)
 
+    // Appending .0 to a prerelease gives its immediate successor, so two
+    // exclusive bounds around that pair cannot contain any version.
+    if ((this.operator === '>' && comp.operator === '<' &&
+      comp.semver.version === `${this.semver.version}.0`) ||
+      (this.operator === '<' && comp.operator === '>' &&
+      this.semver.version === `${comp.semver.version}.0`)) {
+      return false
+    }
+
     // Special cases where nothing can possibly be lower
     if (options.includePrerelease &&
       (this.value === '<0.0.0-0' || comp.value === '<0.0.0-0')) {
diff --git a/test/classes/comparator.js b/test/classes/comparator.js
index 477b2ab6..f19bc0d4 100644
--- a/test/classes/comparator.js
+++ b/test/classes/comparator.js
@@ -44,6 +44,21 @@ test('intersect demands another comparator', t => {
   t.end()
 })
 
+test('adjacent prereleases with loose numeric identifiers', t => {
+  const options = { loose: true, includePrerelease: true }
+  for (const [lower, upper] of [
+    ['1.0.0-01', '1.0.0-1.00'],
+    ['1.0.0-0009007199254740992', '1.0.0-9007199254740992.0'],
+    ['1.0.0-9007199254740992', '1.0.0-0009007199254740992.0'],
+  ]) {
+    const a = new Comparator(`>${lower}`, options)
+    const b = new Comparator(`<${upper}`, options)
+    t.notOk(a.intersects(b, options))
+    t.notOk(b.intersects(a, options))
+  }
+  t.end()
+})
+
 test('ANY matches anything', t => {
   const c = new Comparator('')
   t.ok(c.test('1.2.3'), 'ANY matches anything')
diff --git a/test/fixtures/comparator-intersection.js b/test/fixtures/comparator-intersection.js
index 08c4bc08..9bcfb070 100644
--- a/test/fixtures/comparator-intersection.js
+++ b/test/fixtures/comparator-intersection.js
@@ -41,4 +41,16 @@ module.exports = [
   ['<0.1.0', '<0.0.0-0', false],
   ['<0.0.0-0', '<0.1.0', false, true],
   ['<0.1.0', '<0.0.0-0', false, true],
+  // No version lies strictly between a prerelease and its extension by .0.
+  ['>1.0.0-alpha', '<1.0.0-alpha.0', false],
+  ['>1.0.0-alpha', '<1.0.0-alpha.0', false, true],
+  ['>1.0.0-0', '<1.0.0-0.0', false],
+  ['>1.0.0-alpha.1', '<1.0.0-alpha.1.0', false],
+  ['>1.0.0-alpha+left', '<1.0.0-alpha.0+right', false],
+  ['>1.0.0-9007199254740992', '<1.0.0-9007199254740992.0', false],
+  ['>=1.0.0-alpha', '<1.0.0-alpha.0', true],
+  ['>1.0.0-alpha', '<=1.0.0-alpha.0', true],
+  ['>1.0.0-alpha', '<1.0.0-alpha.1', true],
+  ['>1.0.0-alpha', '<1.0.0-alpha.0.0', true],
+  ['>1.0.0-alpha', '<1.0.0-beta.0', true],
 ]
diff --git a/test/fixtures/range-intersection.js b/test/fixtures/range-intersection.js
index 217bee22..86b0063d 100644
--- a/test/fixtures/range-intersection.js
+++ b/test/fixtures/range-intersection.js
@@ -58,4 +58,8 @@ module.exports = [
   ['1.x', '1.3.0 || <1.0.0 >2.0.0', true],
   ['*', '*', true],
   ['x', '', true],
+  ['>1.0.0-alpha <1.0.0-alpha.0', '>=1.0.0-alpha', false],
+  ['>1.0.0-alpha <1.0.0-alpha.0', '>1.0.0-alpha <1.0.0-alpha.0', false],
+  ['>1.0.0-alpha <1.0.0-alpha.0 || 2.0.0', '*', true],
+  ['>1.0.0-alpha <1.0.0-alpha.0 || 2.0.0', '3.0.0', false],
 ]